RESEARCH
From human to mouse - and back
What can a high-density bone disease (ADO2) teach us about bone cell sigaling? ADO2 is a bone disease caused by genetic mutations in bone cells. ADO2 patients have more bone than healthy individuals. But their bones are still fragile. No cure is available for ADO2-patients
Xenia Borggaard
Post-doc
Molecular Bone Histology
Danish Spatial Imaging Consortium
Syddansk Universitet
Unraveling the complexities of bone cancer and bone pain
My primary research focuses are the multiple myeloma, bone innervation in healthy and disease bone, and the influence of the bone marrow microenvironment to tumorigenesis. Through animal models and advanced histology of patient bone biopsies (ie. Spatial transcriptomics, 3D imaging and AI-assisted analyses), my goal is to target the pre-metastatic pro-tumorigenic niche to prevent bone cancer development in high-risk populations
Marta Diaz-delCastillo
Assistant Professor
Hematology and Bone Histology
Aarhus University
Publications
2023 Dec
Bone
Solene G. D. Hegarty-Cremer, Xenia G. Borggaard, Christina M. Andreasen, Bram C. J. van der Eerden, Matthew J. Simpson, Thomas L. Andersen, Pascal R. Buenzli
2023 Nov
Cancers
Martin Johansen, Mette Bøegh Levring, Kasper Stokbro, Marta Diaz-delCastillo, Abdul Ahad Khan, Line Adsbøll Wickstroem, Michael Tveden Gundesen, Ida Bruun Kristensen, Charlotte Guldborg Nyvold, Mikkel Østerheden Andersen, Thomas Levin Andersen, Niels Abildgaard, and Thomas Lund
2023 Aug
Bone
Andreasen CM, El-Masri BM, MacDonald B, Laursen KS, Nielsen MH, Thomsen JS, Delaisse JM, Andersen TL
2023 Jul
J Neuroscience
Diaz-delCastillo M, Palasca O, Nemler T, Thygesen D, Chávez-Saldaña N, Vázquez-Mora J, Gomez LP, Jensen L, Evans H, Andrews R, Mandal A, Neves D, Mehlen P, Caruso J, Dougherty P, Price T, Chantry A, Lawson M, Andersen TL, Jimenez-Andrade J, Heegaard AM
2023 Jul
Bone Reports
DDrejer LA, El-Masri BM, Ejersted C, Andreasen CM, Thomsen LK, Thomsen JS, Andersen TL, Hansen S
2023 Jun
J Bone Miner Res
Andersen TL, Jensen PR, Sikjaer TT, Rejnmark L, Ejersted C, Delaisse JM
2023 Apr
Nat Commun
Chen L, Shi K, Ditzel N, Qiu W, Figeac F, Nielsen L, Tencerova M, Kowal J, Ding M, Andreasen CM, Andersen TL, Kassem
2023 Mar
J Bone Miner Res
Diaz-del Castillo M, Gundesen MT, Andersen CW, Nielsen AL, Møller HEH, Vinholt PJ, Asmussen JT, Kristensen IB, Nyvold CG, Abildgaard N, Andersen TL, Lund T
2023 Jan
Eur J Endocrinol
Hansen MS, Søe K, Christensen LL, Fernandez-Guerra P, Hansen NW, Wyatt RA, Martin C, Hardy RS, Andersen TL, Olesen JB, Hartmann B, Rosenkilde MM, Kassem M, Rauch A, Gorvin CM, Frost M
2022 Aug
EMBO Mol Med
Fell CW, Hagelkruys A, Cicvaric A, Horrer M, Liu L, Li JSS, Stadlmann J, Polyansky AA, Mereiter S, Tejada MA, Kokotović T, Achuta VS, Scaramuzza A, Twyman KA, Morrow MM, Juusola J, Yan H, Wang J, Burmeister M, Choudhury B, Andersen TL, Wirnsberger G, Holmskov U, Perrimon N, Žagrović B, Monje FJ, Moeller JB, Penninger JM and Nagy V
2022 Jun
Frontiers in Molecular Biosciences
Borggaard X, Nielsen M, Delaisse JM, Andreasen CM, Andersen TL
2022 May
Frontiers in Pain Research
Hansen RB, Sayilekshmy M, Sørensen MS, Jørgensen AH, Kanneworff IB, Bengtsson E, Grum-Schwensen TA, Petersen MM, Ejersted C, Andersen TL, Andreasen CM, Heegaard A
2022 Apr
Bone
Borggaard XG, Roux JP, Delaisse JM, Chavassieux P, Andreasen CM, Andersen TL
2022 Mar
Bone
Lamarche BA, Thomsen JS, Andreasen CM, Lievers WB, Andersen TL
2022 Feb
Stem Cells
Figeac F, Tencerova M, Ali D, Andersen TL, Appadoo DRC, Kerckhofs G, Ditzel N, Kowal JM, Rauch A, Kassem M
2021 Dec
Andersen TL, Delaisse J-M, Thomsen JS, Andreasen CM
2021 Nov
Front Cardiovasc Med
Pilecki B, de Carvalho PVSD, Kirketerp-Møller KL, Schlosser A, Kejling K, Dubik M, Madsen NP, Stubbe J, Hansen PBL, Andersen TL, Moeller JB, Marcussen N, Azevedo V, Hvidsten S, Baun C, Shi GP, Lindholt JS, Sorensen GL
2021 Sept
Frontiers in Endocrinology, section Bone Research
Lucas S, Tencerova M, von der Weid BC, Andersen TL, Attane C, Behler-Janbeck F, Cawthorn WP, Ivaskac KK, Naveiras O, Podgorski I, Reagan MR, van der Eerden BCJ
2021 Aug
Nat Commun.
Nilsson KH, Henning P, Shahawy ME, Nethander M,Andersen TL, Ejersted C, Wu J, Gustafsson KL, Koskela A, Tuukkanen J, Souza PPC, Tuckermann J, Lorentzon M, Ruud LE, Lehtimäki T, Tobias JH, Zhou S, Lerner UH, Richards JB, Movérare- SkrticS, Ohlsson C
2021 May
J Biomech
Yan C, Song H, Pfister J, Andersen TL, Warden SJ, Bhargava R, Kersh ME
2021 April
Br. J. Cancer
Jafari A, Fairfield H, Andersen TL, Reagan M
2021 Apr
Bone
Jensen PR, Andersen TLS, Chavassieux P, Roux JP, Delaisse JM
2021 Apr
PLoS One
Kristensen HB, Andersen TLS, Patriarca A, Kallenbach K, MacDonald B, Sikjaer T, Ejersted C, Delaisse JM
2021 Mar
Cancers (Basel)
Diaz-delCastillo M, Andrews RE, Mandal A, Andersen TL, Chantry AD, Heegaard AM
2021 Mar
J Theor Biol
Hegarty-Cremer SGD, Simpson MJ, Andersen TL, Buenzli PR
2021 Mar
Front Cell Dev Biol
Delaissé JM, Søe K, Andersen TL, Rojek AM, Marcussen N
2021 Jan
PlosOne
Clabaut A, Grare C, Rolland-Valognes G, Letarouilly JG, Bourrier C, Andersen TL, Sikjær T, Rejnmark L, Ejersted C, Pastoureau P, Hardouin P, Sabatini M, Broux O
2020 Dec
Bone
Delaisse JM, Andersen TLS, Kristensen HB, Jensen PR, Andreasen CM, Søe K
2020 Aug
J Bone Miner Res
Brun J, Andreasen CM, Ejersted C, Andersen TL, Caverzasio J, Thouverey C
2020 Mar
Bone
Frost M, Rahbek ET, Ejersted C, Høilund-Carlsen PF, Bygum A, Thomsen JS, Andreasen CM, Andersen TL, Frederiksen AL
2020 Mar
Hepatology
Terkelsen MK, Bendixen SM, Hansen D, Scott EAH, Moeller AF, Nielsen R, Mandrup S, Schlosser A, Andersen TL, Sorensen GL, Krag A, Natarajan KN, Detlefsen S, Dimke H, Ravnskjaer K
2020 Feb
Cancer Res
Fairfield H, Dudakovic A, Khatib CM, Farrell M, Costa S, Falank C, Hinge M, Murphy CS, DeMambro V, Pettitt JA, Lary CW, Driscoll HE, McDonald MM, Kassem M, Rosen C, Andersen TL, van Wijnen AJ, Jafari A, Reagan MR
2020 Jan
JBMR Plus
Ross RD, Anderson K, Davison R, El‐Masri BM, Andreasen CM, Andersen TL, Sumner DR.
2020 Jan
Nat. Commun.
Weivoda MM, Chew CK, Monroe DG, Farr JN, Atkinson EJ, Geske JR, Eckhardt B, Thicke B, Ruan M, Tweed AJ, McCready LK, Rizza RA, Matveyenko A, Kassem M, Andersen TL, Vella A, Drake MT, Clarke BL,Oursler MJ, Khosla S
2019 Nov
Bone
Andreasen CM, Bakalova LP, Brüel A, Hauge EM, Kiil BJ, Delaisse JM, Kersh ME, Thomsen JS, Andersen TL
2019 Nov
Sci Rep
Craft CS, Robles H, Lorenz MR, Hilker ED, Magee KL, Andersen TL, Cawthorn WP, MacDougald OA, Harris CA, Scheller EL
2019 Nov
BMC Med Genomics
Moldovan LI, Hansen TB, Venø MT, Okholm TLH, Andersen TL, Hager H, Iversen L, Kjems J, Johansen C, Kristensen LS
2019 Oct
Calcif Tissue Int
Søe K, Andersen TL, Hinge M, Rolighed L, Marcussen N, Delaisse JM
2019 Mar
Sci Rep.
Sayilekshmy M, Hansen RB, Delaissé JM, Rolighed L, Andersen TL, Heegaard AM
2017 Nov
J. Bone Miner. Res.
Andreasen CM, Delaisse JM, van der Eerden BCJ, van Leeuwen JPTM, Ding M, Andersen TL
2017 Feb
J. Bone Miner. Res.
Lassen NE, Andersen TL, Ploen GG, Søe K, Hauge EM, Harving S, Eschen GET, Delaisse JM